Several Examples of Recent Experimental Research on Interfacing Solid Mechanics and Biomedical Materials or Devices

Lei Yang

Institute of Orthopaedics, Soochow University

Abstract:

Fast evolution of the research on biomedical materials and devices in the past several decades has entered a new interdisciplinary stage that vigorously requires concepts and knowledge of solid mechanics, which provide both fundamental understandings and application insights. This talk begins with a short review of current hot topics on interfacing solids mechanics and biomedical materials, and then focuses on several examples of recent experimental research in this area. In the first example, bone cell filopodial responses and movements on ultra-stiff nano- and micro-topography are investigated by experiment and mechanical simulation, and the crucial implication of the results in biology and nanomedicine is discussed. In the second example, experimental results of surface energy-mediated cell responses and functions are presented, anticipating to establishing a strong correlation between solid surface energy and cellular behavior. In the last example, internal stress evolution in the electric field-induced crystallization in tantalum oxide, which is an energy component of implantable defibrillator, is studied and its importance in increasing lifetime of the biomedical device is discussed.

Bio-Sketch:

Lei Yang received his Ph.D. in Engineering and M.S. in Innovation Management and Entrepreneurship from Brown University, and his M.E. and B.E. in Materials Science and Engineering from Tsinghua University. Before his recent professorship in the Institute of Orthopaedics at Suzhou University, Lei worked as a Lecturer and Postdoc in the School of Engineering at Brown University. His research interests focus on novel biomaterials for orthopedic applications and mechanistic study on cell-material interactions. He has first-authored at least 2 book chapters, 15 peer-reviewed journal papers, 7 conference proceedings and 3 patents. He is a founding editorial member of Nano Bulletin and serves on the review panels of over 25 international research journals. He recently chaired a nanotechnology symposium at the XXI International Materials Research Congress in Mexico. Lei is the recipient of a number of awards, including the Fresh Face Young Scientist of Sigma Xi, the Society For Biomaterials (SFB) Student Award for Outstanding Research, the Materials Research Society (MRS) Graduate Student Silver Award and the Chinese Government Award For Outstanding Students Abroad.

Time:10:00-12:00,September 14th,2012

Venue:1512#,YiFu Technology and Science Building